1-(Dimethoxymethyl)-4-(2-methoxypropan-2-yl)benzene → 116473-61-1
Reaction equation
C[O:2][CH:3](OC)[C:4]1[CH:9]=[CH:8][C:7]([C:10]([O:13][CH3:14])([CH3:12])[CH3:11])=[CH:6][CH:5]=1>O>[CH3:14][O:13][C:10]([C:7]1[CH:6]=[CH:5][C:4]([CH:3]=[O:2])=[CH:9][CH:8]=1)([CH3:12])[CH3:11]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 25 °C
Procedure
1.9 kg of 4-(1-methoxy-1-methylethyl)-benzaldehyde dimethyl acetal and 1.8 kg of water were refluxed (bottom temperature 87° C.) for about 1 hour, while stirring. Thereafter, the mixture was cooled to about 25° C., the phases were separated and the organic phase was distilled under a top pressure of 4 mbar and at 105°-108° C. (top temperatures). This gave 1,314.6 kg of 4-(1-methoxy-1-methylethyl)-benzaldehyde.
Workup
- customthe phases were separated
- distillationthe organic phase was distilled under a top pressure of 4 mbar and at 105°-108° C. (top temperatures)
Sources & evidence
- ORD record
- ord-234fbbfb87784a78b1bcfd32ce5b76bd
- Source dataset
- uspto-grants-1989_07
- Patent number
- US04847425
Reaction notes
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