Toluene → 6-[2-(4-Cyclobutylpiperazin-1-Yl)-2-Oxoethyl]-2-Pyridazin-3-Yl-5,6,7,8-Tetrahydro-1,6-Naphthyridine
Reaction equation
[CH2:25]([Sn:26]([CH2:27][CH2:28][CH2:29][CH3:36])([c:30]1[n:31][n:32][cH:33][cH:34][cH:35]1)[CH2:37][CH2:38][CH2:39][CH3:40])[CH2:41][CH2:42][CH3:43].[CH3:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1.[Cl:1][c:2]1[n:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([CH2:12][C:13](=[O:14])[N:15]1[CH2:16][CH2:17][N:18]([CH:21]3[CH2:22][CH2:23][CH2:24]3)[CH2:19][CH2:20]1)[CH2:6][CH2:5]2.[cH:51]1[cH:52][cH:53][c:54]([P:55]([Pd:56]([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)([P:76]([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[P:95]([c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)([c:114]2[cH:115][cH:116][cH:117][cH:118][cH:119]2)[c:120]2[cH:121][cH:122][cH:123][cH:124][cH:125]2)[cH:126][cH:127]1>>[c:2]1(-[c:30]2[n:31][n:32][cH:33][cH:34][cH:35]2)[n:3][c:4]2[c:9]([cH:10][cH:11]1)[CH2:8][N:7]([CH2:12][C:13](=[O:14])[N:15]1[CH2:16][CH2:17][N:18]([CH:21]3[CH2:22][CH2:23][CH2:24]3)[CH2:19][CH2:20]1)[CH2:6][CH2:5]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-8c0a88cbaecf46318fa8eb4f25e54ba6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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