HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Difluorobenzene → 1,2-Difluorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Difluorobenzene | HCID 9741 | — |
| Reactant | Fluorobenzene | HCID 10008 | — |
| Reactant | Fluorine | HCID 24524 | — |
| Product | 1,2-Difluorobenzene | HCID 9706 | — |
| Product | Fluorobenzene | HCID 10008 | — |
Reaction Steps
According to Sams et al, "Molecular Sieve Fluorination of Fluorobenzene Using Elemental Fluorine," J. Org. Chem. 43(11), 2273 (1978), attempts were made to prepare 1,3-difluorobenzene using a molecular sieve fluorination technique. Fluorination of monofluorobenzene resulted in the isolation of various isomers of difluorobenzene in 19% yield; the highest reported yield for the meta isomer was 1.2%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04847442 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-94ebc396e22e452ca94dedae374927e1 |
| Source note | uspto-grants-1989_07 |