Acetic Acid → tert-Butyl 4-(morpholin-4-yl)piperidine-1-carboxylate

HRID 2316774Notes

Reaction equation

HRID 2316774 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[C:25]([O:26][BH-:27]([O:28][C:29](=[O:30])[CH3:31])[O:32][C:33](=[O:34])[CH3:35])(=[O:36])[CH3:37].[CH2:15]1[CH2:16][O:17][CH2:18][CH2:19][NH:20]1.[CH3:21][C:22](=[O:23])[OH:24].[Cl:39][CH:40]([Cl:41])[CH3:42].[Cl:43][CH2:44][Cl:45].[Na+:38]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:20]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[CH2:12][CH2:13]1

Participants

8

Reactant 7

HCID 176Acetic AcidHCID 923Sodium ionHCID 6344DichloromethaneHCID 63651,1-DichloroethaneHCID 8083MorpholineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylateHCID 2724942Triacetoxyborohydride

Product 1

HCID 14571198tert-Butyl 4-(morpholin-4-yl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-c2d9892746ec4860bd95e81ca4de86d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…