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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2316824Generated: November 2, 2026

Acetic Acid → [(3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amine

https://huagongshe.com/reaction/2316824

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantCyano-borohydrideHCID 498716—
Reactant3-Fluoro-4-(trifluoromethyl)benzaldehydeHCID 2737537—
Reactant[(3RS,4SR)-1-benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-methyl-amineHCID 67324150—
Product[(3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amineHCID 86641315—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-37f2c0d8f28543e99d8d196aef552b1f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)