Bromide ion → 7-Benzyl-4-[4-(5-trifluoromethylpyridin-2-yl)piperazin-1-yl]furo[2,3-d]pyridazine
Reaction equation
[Br-:53].[CH2:54]([c:55]1[cH:56][cH:57][cH:58][cH:59][cH:60]1)[Zn+:61].[Cl:1][c:2]1[n:3][n:4][c:5]([N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]3)[CH2:15][CH2:16]2)[c:6]2[c:7]1[o:8][cH:9][cH:10]2.[Cl:27][c:28]1[n:29][n:30][c:31]([N:32]2[CH2:33][CH2:34][N:35]([c:36]3[cH:37][cH:38][c:39]([C:40]([F:41])([F:42])[F:43])[cH:44][n:45]3)[CH2:46][CH2:47]2)[c:48]2[o:49][cH:50][cH:51][c:52]12>>[c:2]1([CH2:54][c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[n:3][n:4][c:5]([N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]3)[CH2:15][CH2:16]2)[c:6]2[c:7]1[o:8][cH:9][cH:10]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-15d0e0e13d0d47928d8e0dda5a9e915d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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