Ammonia → HCID 14642294, compound

Participants

Reaction Steps

To 22.0 g (0.053 mole) of product from Step A dissolved in 150 ml CHCl3 was added gaseous NH3 at 0°-10° C. for 5 minutes. The reaction mixture was then stirred at room temperature for 2.5 hours. The solvent was then removed in vacuo and the residue was purified by flash chromatography on silica gel eluting with 4% methanol/CHCl3 to give pure title compound, as an oil.

Provenance & Evidence