2-Fluoroethyl bromide → Benzyl 3-[[5-(2,4-dichlorophenyl)-3,6-diethylpyrazin-2-yl]amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate

HRID 2316929Notes

Reaction equation

HRID 2316929 reaction equation
[CH2:32]([c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[O:39][C:40](=[O:41])[N:42]1[CH2:43][CH:44]([NH:48][c:49]2[n:50][c:51]([CH2:65][CH3:66])[c:52](-[c:57]3[c:58]([Cl:64])[cH:59][c:60]([Cl:63])[cH:61][cH:62]3)[n:53][c:54]2[CH2:55][CH3:56])[CH:45]([OH:47])[CH2:46]1.[Cl:1][c:2]1[cH:3][c:4]([Cl:5])[cH:6][cH:7][c:8]1-[c:9]1[n:10][c:11]([CH2:12][CH3:13])[c:14]([NH:15][CH:16]2[c:17]3[c:18]([cH:19][cH:20][cH:21][cH:22]3)[CH2:23][CH:24]2[O:25][CH2:26][CH3:27])[n:28][c:29]1[CH2:30][CH3:31].[F:67][CH2:68][CH2:69][Br:70]>>[CH2:32]([c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[O:39][C:40](=[O:41])[N:42]1[CH2:43][CH:44]([NH:48][c:49]2[n:50][c:51]([CH2:65][CH3:66])[c:52](-[c:57]3[c:58]([Cl:64])[cH:59][c:60]([Cl:63])[cH:61][cH:62]3)[n:53][c:54]2[CH2:55][CH3:56])[CH:45]([O:47][CH2:69][CH2:68][F:67])[CH2:46]1

Participants

4

Reactant 3

HCID 129822-Fluoroethyl bromideHCID 22147271HCID 22147271, compoundHCID 221473105-(2,4-dichlorophenyl)-N-(2-ethoxy-2,3-dihydro-1H-inden-1-yl)-3,6-diethylpyrazin-2-amine

Product 1

HCID 22147410Benzyl 3-[[5-(2,4-dichlorophenyl)-3,6-diethylpyrazin-2-yl]amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-5c60de88ad68403bb3ba819e96462e5e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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