Bicarbonate Ion → HCID 20033706, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of product from Step B, (3.0 g, 8.0 mmol) in CH2Cl2 (132 ml), cooled to -78° C., was added boron tribromide (25.9 ml, 1.0M in CH2Cl2, 25.9 mmol) dropwise and the resulting mixture was stirred at room temperature overnight. The reaction was cooled to 0° C., water and saturated bicarbonate solution added and extracted with ethyl acetate. Drying and solvent evaporation gave a solid (2.9 g); recrystallization from CHCl3 gave the title compound (1.5 g, 52%); m.p. 112°-115° C.

Provenance & Evidence