1H-Pyrazole, 3-methyl-5-(trifluoromethyl)- → 1-[4-(4-Chloro-2-fluoro-5-methoxyphenyl)piperazin-1-yl]-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanone

HRID 2316956Notes

Reaction equation

HRID 2316956 reaction equation
[CH3:21][c:22]1[n:23][nH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1.[Cl:1][CH2:2][C:3](=[O:4])[N:5]1[CH2:6][CH2:7][N:8]([c:11]2[cH:12][c:13]([O:19][CH3:20])[c:14]([Cl:18])[cH:15][c:16]2[F:17])[CH2:9][CH2:10]1>>[CH2:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][N:8]([c:11]2[cH:12][c:13]([O:19][CH3:20])[c:14]([Cl:18])[cH:15][c:16]2[F:17])[CH2:9][CH2:10]1)[n:23]1[c:22]([CH3:21])[cH:26][c:25]([C:27]([F:28])([F:29])[F:30])[n:24]1

Participants

3

Reactant 2

HCID 1390771H-Pyrazole, 3-methyl-5-(trifluoromethyl)-HCID 576427782-Chloro-1-[4-(4-chloro-2-fluoro-5-methoxyphenyl)piperazin-1-yl]ethan-1-one

Product 1

HCID 578404751-[4-(4-Chloro-2-fluoro-5-methoxyphenyl)piperazin-1-yl]-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanone

Sources & evidence

ORD record
ord-75e9d6aab96845f7b468e0e093b3cb4f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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