HCID 86742048, compound → HCID 86742047, compound

HRID 231698Notes

Reaction equation

HRID 231698 reaction equation
[Br:1][C:2]1[N:16]([Si:17]([C:30]([CH3:33])([CH3:32])[CH3:31])([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:15]2[C:34]3[C:3]=1[CH2:4][C@@H:5]1[C@@H:10]([C:11]=3[CH:12]=[CH:13][CH:14]=2)[CH2:9][C@H:8]([NH:35][C:36](=[O:42])[N:37]([CH2:40][CH3:41])[CH2:38][CH3:39])[CH2:7][N:6]1[CH3:43]>C(Cl)(Cl)Cl>[Br:1][C:2]1[N:16]([Si:17]([C:30]([CH3:33])([CH3:31])[CH3:32])([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:15]2[C:34]3[C:3]=1[CH2:4][C@@H:5]1[C:10]([C:11]=3[CH:12]=[CH:13][CH:14]=2)=[CH:9][C@H:8]([NH:35][C:36](=[O:42])[N:37]([CH2:38][CH3:39])[CH2:40][CH3:41])[CH2:7][N:6]1[CH3:43]

Participants

3

Reactant 1

HCID 86742048HCID 86742048, compound

Product 1

HCID 86742047HCID 86742047, compoundYield 19%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

3-[2-bromo-1-(tert-butyldiphenylsilyl)-6-methyl-8α-ergolinyl]-1,1-diethylurea, yield: 19%, [α]D =-0.6° (0.5% in chloroform);

Sources & evidence

ORD record
ord-449cfe48ebfb4f5dbb6a460b85616537
Source dataset
uspto-grants-1989_07
Patent number
US04847262

Reaction notes

Loading…