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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2316980Generated: October 31, 2026

Hydrochloric Acid → 1-{2-Fluoro-3-[3-(trifluoromethyl)pyrrolidin-1-yl]phenyl}-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one

https://huagongshe.com/reaction/2316980

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPalladiumHCID 23938—
Reactant1,4-DioxaneHCID 31275—
ReactantDibenzylidene acetoneHCID 95417—
Reactant3-(Trifluoromethyl)pyrrolidineHCID 5152159—
Reactant1-(3-Bromo-2-fluorophenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-oneHCID 58072344—
Product1-{2-Fluoro-3-[3-(trifluoromethyl)pyrrolidin-1-yl]phenyl}-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-oneHCID 58072225—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-cbd75073e6e643afb303d4a73354f215
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)