tert-butyl 2-(tert-butylcarbamoyl)-3-hydroxypyrrolidine-1-carboxylate → benzyl N-[4-amino-1-[[4-[2-(tert-butylcarbamoyl)-3-hydroxypyrrolidin-1-yl]-3-hydroxy-4-oxo-1-phenylbutan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamate
Reaction equation
[C:1]([O:2][C:6](=[O:7])[N:8]1[CH:9]([C:10](=[O:11])[NH:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH:17]([OH:20])[CH2:18][CH2:19]1)([CH3:3])([CH3:4])[CH3:5].[CH2:21]([c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[O:28][C:29](=[O:30])[NH:31][CH:32]([CH2:33][C:34]([NH2:35])=[O:36])[C:37](=[O:38])[NH:39][CH:40]([CH:41]([C:42]([OH:43])=[O:44])[OH:45])[CH2:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1>>[C:6](=[O:7])([N:8]1[CH:9]([C:10](=[O:11])[NH:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH:17]([OH:20])[CH2:18][CH2:19]1)[CH:41]([CH:40]([NH:39][C:37]([CH:32]([NH:31][C:29]([O:28][CH2:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)=[O:30])[CH2:33][C:34]([NH2:35])=[O:36])=[O:38])[CH2:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1)[OH:45]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-36b273da5ceb44e29d5ec977c7b010a0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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