Ethanol → 3-(3-hydroxy-cyclopentyl)-2-(4-methanesulfonyl-phenyl)-N-thiazol-2-yl-propionamide

HRID 2317054Notes

Reaction equation

HRID 2317054 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8]([CH:11]([C:12](=[O:13])[NH:14][c:15]2[s:16][cH:17][cH:18][n:19]2)[CH2:20][CH:21]2[CH2:22][CH:23]([O:26][CH:27]3[CH2:28][CH2:29][CH2:30][CH2:31][O:32]3)[CH2:24][CH2:25]2)[cH:9][cH:10]1.[CH3:50][CH2:51][OH:52].[c:33]1([CH3:34])[cH:35][cH:36][c:37]([S:38]([O-:39])(=[O:40])=[O:41])[cH:42][cH:43]1.[nH+:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8]([CH:11]([C:12](=[O:13])[NH:14][c:15]2[s:16][cH:17][cH:18][n:19]2)[CH2:20][CH:21]2[CH2:22][CH:23]([OH:26])[CH2:24][CH2:25]2)[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 702EthanolHCID 85570p-ToluenesulfonateHCID 4989215PyridiniumHCID 219589652-(4-methanesulfonyl-phenyl)-3-[3-(tetrahydropyran-2-yloxy)-cyclopentyl]-N-thiazol-2-yl-propionamide

Product 1

HCID 99779543-(3-hydroxy-cyclopentyl)-2-(4-methanesulfonyl-phenyl)-N-thiazol-2-yl-propionamide

Sources & evidence

ORD record
ord-12e47201c6ae4938a8d6970f4ccd89dc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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