2-Cyclopropylmethyl-4-methoxycarbonyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one → 4-carboxy-2-cyclopropylmethyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one

HRID 2317225Notes

Reaction equation

HRID 2317225 reaction equation
[CH:26]1([CH2:29][n:30]2[n:31][c:32](-[c:41]3[cH:42][cH:43][c:44]([S:47][CH3:48])[cH:45][cH:46]3)[cH:33][c:34]([C:37](=[O:38])[O:39][CH3:40])[c:35]2=[O:36])[CH2:27][CH2:28]1.[F:1][c:2]1[cH:3][c:4]([F:5])[cH:6][cH:7][c:8]1-[c:9]1[cH:10][c:11]([CH2:12][O:13][S:14]([CH3:15])(=[O:16])=[O:17])[c:18](=[O:19])[n:20]([CH2:21][CH:22]([CH3:23])[CH3:24])[n:25]1>>[CH:26]1([CH2:29][n:30]2[n:31][c:32](-[c:41]3[cH:42][cH:43][c:44]([S:47][CH3:48])[cH:45][cH:46]3)[cH:33][c:34]([C:37](=[O:38])[OH:39])[c:35]2=[O:36])[CH2:27][CH2:28]1

Participants

3

Reactant 2

HCID 129717712-Cyclopropylmethyl-4-methoxycarbonyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-oneHCID 219914166-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one

Product 1

HCID 219914244-carboxy-2-cyclopropylmethyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one

Sources & evidence

ORD record
ord-5c0b944ff4b2472a8e3b5d990d5505f7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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