Ammonium Chloride → HCID 20034084、化合物

HRID 231725ノート

反応式

HRID 231725 の反応式
C[Mg]Br.[CH3:4]COCC.[CH3:9][C:10]1([CH3:18])[CH2:14][CH2:13][C:12]([CH3:16])([CH3:15])[C:11]1=[O:17].[Cl-].[NH4+]>CCOCC>[CH3:4][C:11]1([OH:17])[C:12]([CH3:16])([CH3:15])[CH2:13][CH2:14][C:10]1([CH3:18])[CH3:9]

参加物

5

反応物 3

HCID 25517Ammonium ChlorideHCID 1382872,2,5,5,-TetramethylcyclopentanoneHCID 178467822HCID 178467822、化合物

生成物 1

HCID 20034084HCID 20034084、化合物

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒2 回

実験手順

100 ml of a 3M methylmagnesium bromide/ether solution was added to a solution of 30 g of 2,2,5,5-tetramethylcyclopentanone in 50 ml of ether under a nitrogen gas atmosphere, and the mixture was stirred at room temperature overnight. Then, 65 ml of aqueous saturated ammonium chloride solution was added dropwise thereto and the mixture was stirred for 10 minutes. The ether layer was subjected to decantation and the residue was extracted with ether. The ether layers were dried over anhydrous sodium sulfate, and concentrated under reduced pressure, whereby 30 g of 1,2,2,5,5-pentamethylcyclopentanol was obtained.

後処理

  1. stirringthe mixture was stirred for 10 minutes
  2. extractionthe residue was extracted with ether
  3. dry with materialThe ether layers were dried over anhydrous sodium sulfate
  4. concentrationconcentrated under reduced pressure

出典と根拠

ORDレコード
ord-dd7c47c13d2c4152a34cb7df56ee8fae
出典データセット
uspto-grants-1989_07
特許番号
US04847390

反応ノート

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