HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 231729Generated: October 27, 2026
Thionyl Chloride → 2,2,5,5-Tetramethylcyclopentanecarbonyl chloride
https://huagongshe.com/reaction/231729
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Cyclopentanecarboxylic acid, 2,2,5,5-tetramethyl- | HCID 10197889 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2,2,5,5-Tetramethylcyclopentanecarbonyl chloride | HCID 13906640 | 69% |
Reaction Steps
2.51 g of 2,2,5,5-tetramethylcyclopentanecarboxylic acid was dissolved in 10 ml of toluene, and 2.5 ml of thionyl chloride was added thereto. The mixture was stirred at 80° C. for 3 hours. The reaction solution was concentrated and then distilled under reduced pressure, whereby 2.0 g of 2,2,5,5-tetramethylcyclopentanecarbonyl chloride was obtained. Yield 69%. (b.p. 110°-120° C./60 mmHg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04847390 |
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| Source dataset | uspto-grants-1989_07 |
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| ORD ID | ord-601deb541d284bfda9b0049aeab201e0 |
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| Source note | uspto-grants-1989_07 |
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