Sulfuric Acid → Desloratadine

HRID 2317456Notes

Reaction equation

HRID 2317456 reaction equation
[CH2:1]([O:2][C:3](=[O:4])[N:6]1[CH2:7][CH2:8][C:9](=[C:12]2[c:13]3[c:14]([cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[CH2:15][CH2:16][c:17]3[c:18]2[n:19][cH:20][cH:21][cH:22]3)[CH2:10][CH2:11]1)[CH3:5].[S:28](=[O:29])(=[O:30])([OH:31])[OH:32]>>[NH:6]1[CH2:7][CH2:8][C:9](=[C:12]2[c:13]3[c:14]([cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[CH2:15][CH2:16][c:17]3[c:18]2[n:19][cH:20][cH:21][cH:22]3)[CH2:10][CH2:11]1

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 3957Loratadine

Product 1

HCID 124087Desloratadine

Sources & evidence

ORD record
ord-1b858d1cb7dd4648a1974004a189df62
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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