Acetone → Prednisolone, 1,2-dihydro-9,11-dedihydro-11-desoxy-, 21-acetate(ester)
Reaction equation
[CH2:46]([Cl:47])[Cl:48].[CH3:41][C:42]([CH3:43])=[O:44].[K+:36].[K+:37].[K+:38].[K+:40].[OH-:39].[OH2:45].[OH:1][C:2]1([C:3](=[CH2:4])[O:5][c:6]2[cH:7][cH:8][cH:9][cH:10][cH:11]2)[CH2:12][CH2:13][CH:14]2[CH:15]3[CH2:16][CH2:17][C:18]4=[CH:19][C:20](=[O:30])[CH2:21][CH2:22][C:23]4([CH3:24])[C:25]3=[CH:26][CH2:27][C:28]12[CH3:29].[P:31]([O-:32])([O-:33])([O-:34])=[O:35].[c:49]1([CH3:50])[cH:51][cH:52][cH:53][cH:54][cH:55]1>>[OH:1][C:2]1([C:3](=[O:4])[CH2:5][O:39][C:42]([CH3:43])=[O:44])[CH2:12][CH2:13][CH:14]2[CH:15]3[CH2:16][CH2:17][C:18]4=[CH:19][C:20](=[O:30])[CH2:21][CH2:22][C:23]4([CH3:24])[C:25]3=[CH:26][CH2:27][C:28]12[CH3:29]Participants
9
Sources & evidence
- ORD record
- ord-d6efb10f049b4abebe6269d8db73eafe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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