4-Methoxyphenylhydrazine hydrochloride → Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1)

HRID 231780Notes

Reaction equation

HRID 231780 reaction equation
[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[S:6][CH2:5][CH2:4][CH:3]1[CH2:13][C:14]([OH:16])=[O:15].[ClH:17].CO[C:20]1[CH:25]=[CH:24][C:23]([NH:26][NH2:27])=[CH:22][CH:21]=1>>[Cl:17][C:10]1[CH:11]=[CH:12][C:7]2[S:6][CH2:5][CH2:4][CH:3]([CH2:13][C:14]([OH:16])=[O:15])[C:2](=[O:1])[C:8]=2[CH:9]=1.[ClH:17].[Cl:17][C:20]1[CH:25]=[CH:24][C:23]([NH:26][NH2:27])=[CH:22][CH:21]=1

Participants

4

Reactant 2

HCID 27239044-Methoxyphenylhydrazine hydrochlorideHCID 14578871(5-Oxo-2,3,4,5-tetrahydro-1-benzothiepin-4-yl)acetic acid

Product 2

HCID 71600Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1)HCID 14578873HCID 14578873, compound

Procedure

Substitution in the procedure of Example 4 for the 5-oxo-2,3,4,5-tetrahydro[1]benzothiepine-4-acetic acid and the 4-methoxyphenylhydrazine hydrochloride used therein of 7-chloro-5-oxo-2,3,4,5-tetrahydro[1]benzothiepine-4-acetic acid and 4-chlorophenylhydrazine hydrochloride, respectively, produces 10 chloro-2-(4-chlorophenyl)-4,4a,5,6-hexahydro-[1]benzothiepino[5,4-c]pyridazin-3(2H)-one, melting at 141°-143° C.

Sources & evidence

ORD record
ord-2f50d440eafa464fa62f994ac9bb3b42
Source dataset
uspto-grants-1989_07
Patent number
US04849421

Reaction notes

Loading…