2-(Bromomethyl)-3-chloro-1,4-difluorobenzene → 1-(2-Chloro-3,6-difluorobenzyl)-7-iodo-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one
Reaction equation
[Cl:13][c:14]1[c:15]([CH2:16][Br:17])[c:18]([F:23])[cH:19][cH:20][c:21]1[F:22].[I:1][c:2]1[cH:3][c:4]2[c:5]([n:11][cH:12]1)[NH:6][CH2:7][C:8](=[O:10])[NH:9]2>>[I:1][c:2]1[cH:3][c:4]2[c:5]([n:11][cH:12]1)[NH:6][CH2:7][C:8](=[O:10])[N:9]2[CH2:16][c:15]1[c:14]([Cl:13])[c:21]([F:22])[cH:20][cH:19][c:18]1[F:23]Participants
3
Sources & evidence
- ORD record
- ord-d8fadd88b2e34a73b2e6855bc3d23f4b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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