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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2318009Generated: October 30, 2026

Hydrochloric Acid → 4-[3-(4-Bromothiophen-2-yl)prop-2-enoyl]-1-[(4-chloroquinolin-7-yl)methyl]-3-methylpiperazin-2-one

https://huagongshe.com/reaction/2318009

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
Reactant4-Bromothiophene-2-carbaldehydeHCID 87792—
Reactant3-(4-Bromothiophen-2-yl)acrylic acidHCID 2774452—
Reactant1-[(4-Chloroquinolin-7-yl)methyl]-3-methylpiperazin-2-oneHCID 17985235—
Product4-[3-(4-Bromothiophen-2-yl)prop-2-enoyl]-1-[(4-chloroquinolin-7-yl)methyl]-3-methylpiperazin-2-oneHCID 57209990—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-c294d6eecb8d42b0870516787826409e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)