Sodium borohydride → HCID 15152248, compound

HRID 231819Notes

Reaction equation

HRID 231819 reaction equation
[CH3:1][O:2][C:3](=[O:26])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH2:11][C:12]1[C:21]2[C:16](=[CH:17][C:18]([O:24][CH3:25])=[C:19]([O:22][CH3:23])[CH:20]=2)[CH2:15][CH2:14][N:13]=1.[BH4-].[Na+]>>[CH3:1][O:2][C:3](=[O:26])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH2:11][CH:12]1[C:21]2[C:16](=[CH:17][C:18]([O:24][CH3:25])=[C:19]([O:22][CH3:23])[CH:20]=2)[CH2:15][CH2:14][NH:13]1

Participants

3

Reactant 2

HCID 4311764Sodium borohydrideHCID 15152245HCID 15152245, compound

Product 1

HCID 15152248HCID 15152248, compound

Procedure

The title compound was prepared was described in Example 10 from 2-[(3,4-dihydro-6,7-dimethoxy-1-isoquinolyl)methyl]benzeneacetic acid methyl ester (IXc, Ex. 9) and sodium borohydride, and the oil product was usd in the subsequent reaction without purification.

Workup

  1. customthe oil product was usd in the subsequent reaction without purification

Sources & evidence

ORD record
ord-8da29e754e3e4399a033d82fca74b06d
Source dataset
uspto-grants-1989_07
Patent number
US04849420

Reaction notes

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