2-Bromo-5-methanesulfonylthiophene → [2-Fluoro-4-(5-methylsulfonylthiophen-2-yl)phenyl]-[2-[(2-methylpyrrolidin-1-yl)methyl]pyrrolidin-1-yl]methanone

HRID 2318212Notes

Reaction equation

HRID 2318212 reaction equation
[Br:31][c:32]1[s:33][c:34]([S:37](=[O:38])(=[O:39])[CH3:40])[cH:35][cH:36]1.[F:1][c:2]1[c:3]([C:17](=[O:18])[N:19]2[CH:20]([CH2:24][N:25]3[CH:26]([CH3:30])[CH2:27][CH2:28][CH2:29]3)[CH2:21][CH2:22][CH2:23]2)[cH:4][cH:5][c:6]([B:8]2[O:9][C:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[O:16]2)[cH:7]1>>[F:1][c:2]1[c:3]([C:17](=[O:18])[N:19]2[CH:20]([CH2:24][N:25]3[CH:26]([CH3:30])[CH2:27][CH2:28][CH2:29]3)[CH2:21][CH2:22][CH2:23]2)[cH:4][cH:5][c:6](-[c:32]2[s:33][c:34]([S:37](=[O:38])(=[O:39])[CH3:40])[cH:35][cH:36]2)[cH:7]1

Participants

3

Reactant 2

HCID 173902812-Bromo-5-methanesulfonylthiopheneHCID 76694943[2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-[2-[(2-methylpyrrolidin-1-yl)methyl]pyrrolidin-1-yl]methanone

Product 1

HCID 11640964[2-Fluoro-4-(5-methylsulfonylthiophen-2-yl)phenyl]-[2-[(2-methylpyrrolidin-1-yl)methyl]pyrrolidin-1-yl]methanone

Sources & evidence

ORD record
ord-8282d7d6c29c4632819c763d30d69929
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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