Potassium Cation → (2,4-Difluoro-benzyl)-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-amine

HRID 2318566Notes

Reaction equation

HRID 2318566 reaction equation
[Br:1][CH2:2][CH2:3][O:4][c:5]1[cH:6][c:7](-[c:11]2[n:12][o:13][c:14]3[c:15]2[s:16][cH:17][cH:18]3)[cH:8][cH:9][cH:10]1.[C:19](=[O:20])([O-:21])[O-:22].[CH3:35][C:36]#[N:37].[F:25][c:26]1[c:27]([CH2:28][NH2:29])[cH:30][cH:31][c:32]([F:34])[cH:33]1.[K+:23].[K+:24]>>[CH2:2]([CH2:3][O:4][c:5]1[cH:6][c:7](-[c:11]2[n:12][o:13][c:14]3[c:15]2[s:16][cH:17][cH:18]3)[cH:8][cH:9][cH:10]1)[NH:29][CH2:28][c:27]1[c:26]([F:25])[cH:33][c:32]([F:34])[cH:31][cH:30]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 27332442,4-DifluorobenzylamineHCID 219835823-[3-(2-Bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole

Product 1

HCID 21983597(2,4-Difluoro-benzyl)-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-amine

Sources & evidence

ORD record
ord-26bc4f19d129499b9cf702108b589157
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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