HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2-Thenylamine, N,N-bis(2-chloroethyl)-, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Acetic acid 10-acetoxymethyl-anthracen-9-ylmethyl ester | HCID 613145 | — |
| Reactant | HCID 131715389 | HCID 131715389 | — |
| Solvent | Oxygen | HCID 977 | — |
| Product | 2-Thenylamine, N,N-bis(2-chloroethyl)-, hydrochloride | HCID 203604 | — |
Reaction Steps
One millimole of DCTA-bromide was added to 5 ml of DMF containing 0.2 ml of 1,2-dithioethylene and 0.5 ml of triethylamine. The mixture was incubated under argon for 2 hours at 60°-70° C. After reaction the mixture was diluted with oxygen-free H2O to 50 ml, the pH was adjusted to 4.0-4.5 with glacial acetic
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04849505 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-000a47c865de4642a35a7aa65463289b |
| Source note | uspto-grants-1989_07 |