1-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol → Methyl 3-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate
Reaction equation
[Br:1][c:2]1[n:3][c:4]([CH2:5][CH3:6])[c:7]([NH:8][CH:9]2[c:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[CH2:16][CH:17]2[OH:18])[n:19][c:20]1[CH2:21][CH3:22].[CH2:23]([CH3:24])[c:25]1[c:26]([NH:33][CH:34]2[CH2:35][N:36]([C:43](=[O:44])[O:45][CH3:46])[CH2:37][CH:38]2[O:39][CH2:40][CH2:41][F:42])[n:27][c:28]([CH2:31][CH3:32])[cH:29][n:30]1>>[Br:1][c:29]1[c:28]([CH2:31][CH3:32])[n:27][c:26]([NH:33][CH:34]2[CH2:35][N:36]([C:43](=[O:44])[O:45][CH3:46])[CH2:37][CH:38]2[O:39][CH2:40][CH2:41][F:42])[c:25]([CH2:23][CH3:24])[n:30]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-99dbe66697eb43ce9222b95cfeb5e883
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…