HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2318934Generated: October 27, 2026
Tetrahydrofuran → 1-{[Tert-butyl(dimethyl)silyl]oxy}-2-(5-{3-[(4-cyclopropyl-5-fluoropyrimidin-2-yl)amino]-5-fluorophenyl}-1,3-thiazol-2-yl)propan-2-ol
https://huagongshe.com/reaction/2318934
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Lithium ion | HCID 28486 | — |
| Reactant | 1-(tert-Butyldimethylsilyloxy)-2-propanone | HCID 4124969 | — |
| Reactant | Diisopropylamide | HCID 5062348 | — |
| Reactant | 4-cyclopropyl-5-fluoro-N-[3-fluoro-5-(1,3-thiazol-5-yl)phenyl]pyrimidin-2-amine | HCID 67257916 | — |
| Product | 1-{[Tert-butyl(dimethyl)silyl]oxy}-2-(5-{3-[(4-cyclopropyl-5-fluoropyrimidin-2-yl)amino]-5-fluorophenyl}-1,3-thiazol-2-yl)propan-2-ol | HCID 67261191 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (10/10) |
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| ORD ID | ord-f571730813224f5d9229b0f5c26eb228 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (10/10) |
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