HRID231899

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C=CCOC(=O)N1CCC[C@@H](OC)[C@@H]1CC(=O)CBr

HCID86741991

未命名化合物

HCID135703883

4-Oxo-1,4-dihydroquinazoline-6-carbonitrile

C9H5N3O

PRODUCTS

生成物

结构：C=CCOC(=O)N1CCC[C@@H](OC)[C@@H]1CC(=O)Cn1cnc2ccc(C#N)cc2c1=O

HCID86742324

未命名化合物

收率 49%

PROCEDURE

实验过程

By the method of Example 4, 6-cyanoquinazolin-4(3H)-one and allyl trans-2-(3-bromo-2-oxopropyl)-3-methoxypiperidine-1-carboxylate were converted to title compound in 49% yield; 1H-NMR(CDCl3) 1.2-1.9 (m, 4H), 2.9 (d, 2H), 2.9-3.5 (m, 4H), 4.6-6.2 (m, 5H), 5.2 (s, 2H), 7.8-8.6 (m, 4H).