Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4,6-Dichloro-5-(4-methylphenyl)pyrimidine → 5-(4-Methylphenyl)-4,6-dichloro-2-phenylpyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4,6-Dichloro-5-(4-methylphenyl)pyrimidine | HCID 21979554 | — |
| 반응물 | HCID 178418453 | HCID 178418453 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 5-(4-Methylphenyl)-4,6-dichloro-2-phenylpyrimidine | HCID 19689470 | — |
반응 단계
A solution of 5-(4-methylphenyl)-4,6-dichloropyrimidine in ether is cooled at -30° C., and thereto is added dropwise a 1.8M phenyl lithium/cyclohexane solution. The reaction mixture is treated in the same manner as in Reference Example 20-(1) to give 5-(4-methylphenyl)-4,6-dichloro-2-phenylpyrimidine as crystalline powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728706 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-92159ddf5fca43a09bd60ede97b3d342 |
| 출처 메모 | uspto-grants-1998_03 |