4,6-Di(propan-2-yl)benzene-1,3-diamine → HCID 14573497, compound

Participants

Reaction Steps

A suitable autoclave was charged with 20.7 g (0.108 mol) of purified 1,3-diamino-4,6-diisopropylbenzene, 0.3 g (2.7 mmol) of potassium t-butoxide, 2.0 g of 5% Ru on alumina, and 100 mL of t-butanol. The autoclave was heated to 190° C. at 25.5 MPa hydrogen for 24 hours. It was then cooled and its contents filtered. The solvent was removed from the filtrate in vacuo and the resulting liquid distilled through a 20.3 cm Vigreaux column at about 4 mm Hg/115°-118° C. to give 5.9 g (28%) of 1,3-diamino-4,6-diisopropylcyclohexane.

Provenance & Evidence