(1,5-dimethyl-1H-pyrrol-2-yl)methanamine → N-((1,5-dimethyl-1H-pyrrol-2-yl)methyl)-5-(3-(4-fluorobenzyl)-2-oxoimidazolidin-1-yl)-3-methylthiophene-2-carboxamide

HRID 2319254Notes

Reaction equation

HRID 2319254 reaction equation
[CH3:1][c:2]1[cH:3][c:4]([N:5]2[CH2:6][CH2:7][N:8]([CH2:9][CH2:10][O:11][c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[C:18]2=[O:19])[s:20][c:21]1[C:22]([OH:23])=[O:24].[CH3:48][n:49]1[c:50]([CH2:55][NH2:56])[cH:51][cH:52][c:53]1[CH3:54].[F:25][c:26]1[cH:27][cH:28][c:29]([CH2:30][N:31]2[C:32](=[O:45])[N:33]([c:36]3[cH:37][c:38]([CH3:44])[c:39]([C:41](=[O:42])[OH:43])[s:40]3)[CH2:34][CH2:35]2)[cH:46][cH:47]1>>[F:25][c:26]1[cH:27][cH:28][c:29]([CH2:30][N:31]2[C:32](=[O:45])[N:33]([c:36]3[cH:37][c:38]([CH3:44])[c:39]([C:41](=[O:42])[NH:56][CH2:55][c:50]4[n:49]([CH3:48])[c:53]([CH3:54])[cH:52][cH:51]4)[s:40]3)[CH2:34][CH2:35]2)[cH:46][cH:47]1

Participants

4

Reactant 3

HCID 737232(1,5-dimethyl-1H-pyrrol-2-yl)methanamineHCID 580314563-Methyl-5-(2-oxo-3-(2-phenoxyethyl)imidazolidin-1-yl)thiophene-2-carboxylic acidHCID 580314655-(3-(4-Fluorobenzyl)-2-oxoimidazolidin-1-yl)-3-methylthiophene-2-carboxylic acid

Product 1

HCID 25097190N-((1,5-dimethyl-1H-pyrrol-2-yl)methyl)-5-(3-(4-fluorobenzyl)-2-oxoimidazolidin-1-yl)-3-methylthiophene-2-carboxamide

Sources & evidence

ORD record
ord-66cae6d5744f431fa97a4a95351bf489
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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