Thiophosgene → HCID 57168133, compound

Participants

Reaction Steps

A solution of sodium hydroxide (1.01 g) in 2 ml of water was added to a cool (10° C. or below) solution of 5.50 g of S-(4-methoxyphenyl) 4-(hydroxy)thiobenzoate and 2.42 ml of thiophosgene in 75 ml of chloroform. Vigorous stirring was continued for 2 hours at room temperature and the filtered solution treated with calcium chloride for a further 30 minutes. Evaporation of the filtered solution and chromatography of the residue on silica gel using hexane/ethyl acetate mixtures as eluant gave 2.75 g of the title compound.

Provenance & Evidence