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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2319662Generated: November 2, 2026

Trifluoroacetic acid → racemic (2'R,3R,4'S)-6-chloro-4'-(3-chlorophenyl)-2'-isopropenyl-1'-(3-piperidin-1-yl-propyl) spiro[3H-indole-3,3' piperidine]-2,6'(1H)-dione

https://huagongshe.com/reaction/2319662

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantPiperidineHCID 8082—
Reactant(1-Methoxyethyl)(trimethyl)silaneHCID 22400412—
Reactant6-chloro-4'-(3-chlorophenyl)-1'-(3-chloropropyl)-6'-prop-1-en-2-ylspiro[1H-indole-3,5'-piperidine]-2,2'-dioneHCID 77580065—
Productracemic (2'R,3R,4'S)-6-chloro-4'-(3-chlorophenyl)-2'-isopropenyl-1'-(3-piperidin-1-yl-propyl) spiro[3H-indole-3,3' piperidine]-2,6'(1H)-dioneHCID 76568019—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-a1398595c05e4d38976faa0a54f550ea
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)