(4-Methylpiperazin-2-yl)methanol → 5-[[1-[[2,4-Bis(trifluoromethyl)phenyl]methyl]indazol-5-yl]methylidene]-2-[2-(hydroxymethyl)-4-methylpiperazin-1-yl]-1,3-thiazol-4-one

HRID 2319863Notes

Reaction equation

HRID 2319863 reaction equation
[CH3:35][N:36]1[CH2:37][CH:38]([CH2:42][OH:43])[NH:39][CH2:40][CH2:41]1.[F:1][C:2]([c:3]1[c:4]([CH2:5][n:6]2[n:7][cH:8][c:9]3[cH:10][c:11]([CH:15]=[C:16]4[C:17](=[O:24])[N:18]=[C:19]([S:21][CH2:22][CH3:23])[S:20]4)[cH:12][cH:13][c:14]23)[cH:25][cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]1)([F:33])[F:34]>>[F:1][C:2]([c:3]1[c:4]([CH2:5][n:6]2[n:7][cH:8][c:9]3[cH:10][c:11]([CH:15]=[C:16]4[C:17](=[O:24])[N:18]=[C:19]([N:39]5[CH:38]([CH2:42][OH:43])[CH2:37][N:36]([CH3:35])[CH2:41][CH2:40]5)[S:20]4)[cH:12][cH:13][c:14]23)[cH:25][cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]1)([F:33])[F:34]

Participants

3

Reactant 2

HCID 12793177(4-Methylpiperazin-2-yl)methanolHCID 866545405-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one

Product 1

HCID 767563055-[[1-[[2,4-Bis(trifluoromethyl)phenyl]methyl]indazol-5-yl]methylidene]-2-[2-(hydroxymethyl)-4-methylpiperazin-1-yl]-1,3-thiazol-4-one

Sources & evidence

ORD record
ord-d098e4d7e4874684a27f00fad2010bba
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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