1,3-Dihydro-1,3-dioxo-2H-isoindole-2-butanal → 7-Methoxy-2-(4-phthalimidobutyl)-1,2,3,4-tetrahydroisoquinoline

HRID 2319916Notes

Reaction equation

HRID 2319916 reaction equation
[C:1]1(=[O:16])[c:2]2[c:3]([cH:12][cH:13][cH:14][cH:15]2)[C:4](=[O:11])[N:5]1[CH2:6][CH2:7][CH2:8][CH:9]=[O:10].[CH3:17][O:18][c:19]1[cH:20][cH:21][c:22]2[c:27]([cH:28]1)[CH2:26][NH:25][CH2:24][CH2:23]2>>[C:1]1(=[O:16])[c:2]2[c:3]([cH:12][cH:13][cH:14][cH:15]2)[C:4](=[O:11])[N:5]1[CH2:6][CH2:7][CH2:8][CH2:9][N:25]1[CH2:24][CH2:23][c:22]2[cH:21][cH:20][c:19]([O:18][CH3:17])[cH:28][c:27]2[CH2:26]1

Participants

3

Reactant 2

HCID 771501,3-Dihydro-1,3-dioxo-2H-isoindole-2-butanalHCID 4172887-Methoxy-1,2,3,4-Tetrahydroisoquinoline

Product 1

HCID 221325287-Methoxy-2-(4-phthalimidobutyl)-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-b20973f4e0b647b7adcf129f9f349d9b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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