4-Acetylpyridine → HCID 86743254, compound

HRID 232029Notes

Reaction equation

HRID 232029 reaction equation
[NH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][CH2:11][C:12](=[O:15])[NH:13][N:14]=2)=[CH:5][CH:4]=1)[NH2:2].[C:16]([C:19]1[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=1)(=O)[CH3:17]>>[O:15]=[C:12]1[CH2:11][O:10][C:9]([C:6]2[CH:5]=[CH:4][C:3]([NH:1][N:2]=[C:16]([C:19]3[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=3)[CH3:17])=[CH:8][CH:7]=2)=[N:14][NH:13]1

Participants

3

Reactant 2

HCID 142824-AcetylpyridineHCID 14742849HCID 14742849, compound

Product 1

HCID 86743254HCID 86743254, compound

Procedure

Analogously to Example 2 (a), from the so obtained amine there is prepared 2-(4-hydrazinophenyl)-4,5-dihydro-6H-1,3,4-oxadiazin-5-one and the suspension obtained after reduction thereof is mixed, without isolation of the hydrozine, with the 4-acetylpyridine. The reaction mixture is further stirred for 3 hours with suction and washed with water. There is thus obtained, as a crude product, 4-acetylpyridine-[4-(5-oxo-4,5-dihydro-6H-1,3,4-oxadiazin-2-yl)-phenylhydrazone]; m.p. 195° C.

Workup

  1. customthe suspension obtained after reduction
  2. washwashed with water

Sources & evidence

ORD record
ord-f1d4c557a0644cd18103bf29e6f53e9f
Source dataset
uspto-grants-1989_07
Patent number
US04851406

Reaction notes

Loading…