Methanol → 6-[3-[2-[4-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]ethyl]phenoxy]ethyl-methylcarbamoyl]phenyl]sulfonyl-4-(3-methoxyanilino)-8-methylquinoline-3-carboxamide
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([CH:20]([CH2:21][NH:22][CH2:23][CH2:24][c:25]2[cH:26][cH:27][c:28]([O:29][CH2:30][CH2:31][N:32]([C:33](=[O:34])[c:35]3[cH:36][c:37]([S:41](=[O:42])(=[O:43])[c:44]4[cH:45][c:46]5[c:47]([NH:58][c:59]6[cH:60][c:61]([O:65][CH3:66])[cH:62][cH:63][cH:64]6)[c:48]([C:55](=[O:56])[NH2:57])[cH:49][n:50][c:51]5[c:52]([CH3:54])[cH:53]4)[cH:38][cH:39][cH:40]3)[CH3:67])[cH:68][cH:69]2)[O:70][Si:71]([CH3:72])([CH3:73])[C:74]([CH3:75])([CH3:76])[CH3:77])[c:13]2[cH:14][cH:15][c:16](=[O:19])[nH:17][c:18]12.[CH3:78][OH:79]>>[OH:8][c:9]1[cH:10][cH:11][c:12]([CH:20]([CH2:21][NH:22][CH2:23][CH2:24][c:25]2[cH:26][cH:27][c:28]([O:29][CH2:30][CH2:31][N:32]([C:33](=[O:34])[c:35]3[cH:36][c:37]([S:41](=[O:42])(=[O:43])[c:44]4[cH:45][c:46]5[c:47]([NH:58][c:59]6[cH:60][c:61]([O:65][CH3:66])[cH:62][cH:63][cH:64]6)[c:48]([C:55](=[O:56])[NH2:57])[cH:49][n:50][c:51]5[c:52]([CH3:54])[cH:53]4)[cH:38][cH:39][cH:40]3)[CH3:67])[cH:68][cH:69]2)[O:70][Si:71]([CH3:72])([CH3:73])[C:74]([CH3:75])([CH3:76])[CH3:77])[c:13]2[cH:14][cH:15][c:16](=[O:19])[nH:17][c:18]12Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-9162f118b685403684019904ed87e8b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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