tert-butyl 4-(4-amino-1H-pyrazol-1-yl)piperidine-1-carboxylate → 4-{4-[8-(4-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridine-2-ylamino]-pyrazol-1-yl}-piperidin-1-carboxylic acid tert-butyl ester
Reaction equation
[C:21]([CH3:22])([CH3:23])([CH3:24])[O:25][C:26](=[O:27])[N:28]1[CH2:29][CH2:30][CH:31]([n:34]2[n:35][cH:36][c:37]([NH2:39])[cH:38]2)[CH2:32][CH2:33]1.[CH:40]1([P:41]([CH:42]2[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47]2)[C:48]2([P:49]([CH:50]3[CH2:51][CH2:52][CH2:53][CH2:54][CH2:55]3)[CH:56]3[CH2:57][CH2:58][CH2:59][CH2:60][CH2:61]3)[CH2:62][CH:63]=[CH:64][CH:65]=[C:66]2[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[CH2:73][CH2:74][CH2:75][CH2:76][CH2:77]1.[Cl:1][c:2]1[n:3][n:4]2[c:5]([c:6](-[c:10]3[cH:11][cH:12][c:13]([S:16](=[O:17])(=[O:18])[CH3:19])[cH:14][cH:15]3)[cH:7][cH:8][cH:9]2)[n:20]1>>[c:2]1([NH:39][c:37]2[cH:36][n:35][n:34]([CH:31]3[CH2:30][CH2:29][N:28]([C:26]([O:25][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:27])[CH2:33][CH2:32]3)[cH:38]2)[n:3][n:4]2[c:5]([c:6](-[c:10]3[cH:11][cH:12][c:13]([S:16](=[O:17])(=[O:18])[CH3:19])[cH:14][cH:15]3)[cH:7][cH:8][cH:9]2)[n:20]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-222167b6bc1e4a0a8f657f8afa8c74f7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…