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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2320971Generated: October 30, 2026

Water → 2-amino-5-[4-(difluoromethoxy)phenyl]-5-[3-(3-hydroxyprop-1-yn-1-yl)phenyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one

https://huagongshe.com/reaction/2320971

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPropargyl alcoholHCID 7859—
ReactantPyrrolidineHCID 31268—
Reactant2-amino-4-(3-bromophenyl)-4-(4-(difluoromethoxy)phenyl)-1-methyl-1H-imidazol-5(4H)-oneHCID 59790307—
ReactantHCID 178420554HCID 178420554—
Product2-amino-5-[4-(difluoromethoxy)phenyl]-5-[3-(3-hydroxyprop-1-yn-1-yl)phenyl]-3-methyl-3,5-dihydro-4H-imidazol-4-oneHCID 57435914—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-8e6f951c73464a96ac75fc31e95e08e1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)