Benzenemethanamine, N,N-bis(2-chloroethyl)-4-fluoro- → 4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(4-fluoro-benzyl)-piperidine-4-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][S:6](=[O:7])(=[O:8])[c:9]1[cH:10][cH:11][c:12]([O:15][CH2:16][C:17]#[C:18][CH3:19])[cH:13][cH:14]1)=[O:20].[F:21][c:22]1[cH:23][cH:24][c:25]([CH2:26][N:27]([CH2:28][CH2:29][Cl:33])[CH2:31][CH2:32][Cl:30])[cH:34][cH:35]1>>[CH2:1]([CH3:2])[O:3][C:4]([C:5]1([S:6](=[O:7])(=[O:8])[c:9]2[cH:10][cH:11][c:12]([O:15][CH2:16][C:17]#[C:18][CH3:19])[cH:13][cH:14]2)[CH2:29][CH2:28][N:27]([CH2:26][c:25]2[cH:24][cH:23][c:22]([F:21])[cH:35][cH:34]2)[CH2:31][CH2:32]1)=[O:20]Participants
3
Sources & evidence
- ORD record
- ord-d3cbdee1f47b4080af4b2598fd5a029c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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