HCID 54414628, compound → HCID 14576222, compound

HRID 232155Notes

Reaction equation

HRID 232155 reaction equation
C([O:3][C:4]([C:6]1[C:14]2[CH2:13][CH2:12][CH2:11][CH2:10][C:9]=2[N:8]([C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)[N:7]=1)=[O:5])C>CO>[CH3:22][O:21][C:18]1[CH:19]=[CH:20][C:15]([N:8]2[C:9]3[CH2:10][CH2:11][CH2:12][CH2:13][C:14]=3[C:6]([C:4]([OH:5])=[O:3])=[N:7]2)=[CH:16][CH:17]=1

Participants

3

Reactant 1

HCID 54414628HCID 54414628, compound

Product 1

HCID 14576222HCID 14576222, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 1-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid ethyl ester in methanol (50 ml) was heated at reflux temperature for one hour, cooled, concentrated in vacuo, diluted with water, and acidified. The precipitate was filtered to yield the title compound (0.360 g). An analytical sample (m.p. 233°-234° C.) was obtained from methylene chloride-hexane solution.

Workup

  1. temperatureat reflux temperature for one hour
  2. temperaturecooled
  3. concentrationconcentrated in vacuo
  4. additiondiluted with water
  5. filtrationThe precipitate was filtered

Sources & evidence

ORD record
ord-ef20d6e63bcc478ebbb29e5006ca7115
Source dataset
uspto-grants-1989_07
Patent number
US04851425

Reaction notes

Loading…