HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14576224, compound → HCID 14576225, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14576224 | HCID 14576224 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 14576225 | HCID 14576225 | 66.8% |
Reaction Steps
A toluene (150 ml) solution of the compound of Example 77 (3.0 g) was treated with activated manganese (IV) oxide (9.0 g) and azeotropically distilled during 30 minutes. The hot suspension was filtered and the filtrate evaporated to yield pure title compound (1.99 g). A repeat reaction provided 2.0 g. Crystallization of the combined product from acetonitrile gave 3.80 g, m.p. 120°-121° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04851425 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-50fadb6541b44c47a5ff3255cbc70dec |
| Source note | uspto-grants-1989_07 |