Acetic Anhydride → HCID 131716013, compound

Participants

Reaction Steps

0.2 g of the 9,10-dihydroxy-octadecyl glycerol (III) was dissolved in a small volume of chloroform (0.5 ml) in a screw tube and 2 ml acetic anhydride added. The reaction mixture was placed in a water bath for 2 h at 60° C., then dried down under a nitrogen stream. The residue was redissolved in chloroform:methanol:water (1:2:0.8) (v/v/v) and separated into phases by the addition of the appropriate amounts of chloroform and water to a final ratio of 1:1:0.9 (v/v/v). The synthesized compound (IV) is partioned in the chloroform phase.

Provenance & Evidence