3-(2-Methoxyethyl)-2,3,4,5-tetrahydro-1h-3-benzazepin-7-amine → N-(2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]-pyrimidin-4-ylamino}-propyl)-methanesulfonamide

HRID 2321706Notes

Reaction equation

HRID 2321706 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:12][c:13]([NH2:16])[cH:14][cH:15]2)[CH2:10][CH2:11]1.[Cl:17][c:18]1[n:19][cH:20][c:21]([Cl:33])[c:22]([NH:24][CH:25]([CH2:26][NH:27][S:28](=[O:29])(=[O:30])[CH3:31])[CH3:32])[n:23]1>>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:12][c:13]([NH:16][c:18]3[n:19][cH:20][c:21]([Cl:33])[c:22]([NH:24][CH:25]([CH2:26][NH:27][S:28](=[O:29])(=[O:30])[CH3:31])[CH3:32])[n:23]3)[cH:14][cH:15]2)[CH2:10][CH2:11]1

Participants

3

Reactant 2

HCID 574160893-(2-Methoxyethyl)-2,3,4,5-tetrahydro-1h-3-benzazepin-7-amineHCID 86633870N-[2-(2,5-dichloro-pyrimidin-4-ylamino)-propyl]-methanesulfonamide

Product 1

HCID 66829941N-(2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]-pyrimidin-4-ylamino}-propyl)-methanesulfonamide

Sources & evidence

ORD record
ord-b1769138d6864fa888426447de077c1d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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