Methanesulfonyl chloride → 5-[4-[2-(1-Methylsulfonylpiperidin-2-yl)ethenyl]-2-phenylmethoxyphenyl]-1,1-dioxo-2-(2-trimethylsilylethyl)-1,2,5-thiadiazolidin-3-one

HRID 2321890Notes

Reaction equation

HRID 2321890 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([N:23]2[CH2:24][C:25](=[O:36])[N:26]([CH2:30][CH2:31][Si:32]([CH3:33])([CH3:34])[CH3:35])[S:27]2(=[O:28])=[O:29])[cH:11][cH:12][c:13]([CH:15]=[CH:16][CH:17]2[NH:18][CH2:19][CH2:20][CH2:21][CH2:22]2)[cH:14]1.[CH3:37][S:38]([Cl:39])(=[O:40])=[O:41]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([N:23]2[CH2:24][C:25](=[O:36])[N:26]([CH2:30][CH2:31][Si:32]([CH3:33])([CH3:34])[CH3:35])[S:27]2(=[O:28])=[O:29])[cH:11][cH:12][c:13]([CH:15]=[CH:16][CH:17]2[N:18]([S:38]([CH3:37])(=[O:40])=[O:41])[CH2:19][CH2:20][CH2:21][CH2:22]2)[cH:14]1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 688427251,1-Dioxo-5-[2-phenylmethoxy-4-(2-piperidin-2-ylethenyl)phenyl]-2-(2-trimethylsilylethyl)-1,2,5-thiadiazolidin-3-one

Product 1

HCID 688398425-[4-[2-(1-Methylsulfonylpiperidin-2-yl)ethenyl]-2-phenylmethoxyphenyl]-1,1-dioxo-2-(2-trimethylsilylethyl)-1,2,5-thiadiazolidin-3-one

Sources & evidence

ORD record
ord-41f3d39bd73e46abba18c78fbfd23602
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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