Azane;hydrate → HCID 20030947, compound

Participants

Reaction Steps

In 2.4 ml of concentrated ammonia water was dissolved 150 mg of 4-benzyloxycarbonylamino-5-methoxycarbonyl-3-isoxazolidinone (mixture of 4,5-cis compound and -trans compound). The solution was left standing at room temperature for 20 minutes, which was concentrated to dryness under reduced pressure. Ether was added to the concentrate to give 138 mg of 4-benzyloxycarbonylamino-5-carbamoyl-3-isoxazolidinone as crystals.

Provenance & Evidence