8-[2-amino-1-[tert-butyl(dimethyl)silyl]oxyethyl]-6-hydroxy-4H-1,4-benzoxazin-3-one → 6-[11-[[2-[tert-butyl(dimethyl)silyl]oxy-2-(6-hydroxy-3-oxo-4H-1,4-benzoxazin-8-yl)ethyl]amino]undecylsulfonyl]-4-(3-methoxyanilino)-8-methylquinoline-3-carboxamide
Reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:5][CH:6]([c:7]1[cH:8][cH:9][c:10]([OH:11])[c:12]2[c:13]1[cH:14][cH:15][c:16](=[O:17])[nH:18]2)[CH2:19][NH:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][NH:29][C:30]([c:31]1[cH:32][c:33]([S:34]([c:35]2[cH:36][c:37]3[c:38]([c:39]([CH3:40])[cH:41]2)[n:42][cH:43][c:44]([C:45]([NH2:46])=[O:47])[c:48]3[NH:49][c:50]2[cH:51][cH:52][cH:53][c:54]([O:55][CH3:56])[cH:57]2)(=[O:58])=[O:59])[cH:60][cH:61][cH:62]1)=[O:63])([CH3:64])([CH3:65])[CH3:66].[CH3:90][O:91][c:92]1[cH:93][c:94]([NH:98][c:99]2[c:100]([C:125](=[O:126])[NH2:127])[cH:101][n:102][c:103]3[c:104]([CH3:124])[cH:105][c:106]([S:109](=[O:110])(=[O:111])[CH2:112][CH2:113][CH2:114][CH2:115][CH2:116][CH2:117][CH2:118][CH2:119][CH2:120][CH2:121][CH:122]=[O:123])[cH:107][c:108]23)[cH:95][cH:96][cH:97]1.[NH2:67][CH2:68][CH:69]([O:70][Si:71]([CH3:72])([CH3:73])[C:74]([CH3:75])([CH3:76])[CH3:77])[c:78]1[cH:79][c:80]([OH:89])[cH:81][c:82]2[c:83]1[O:84][CH2:85][C:86](=[O:88])[NH:87]2>>[NH:67]([CH2:68][CH:69]([O:70][Si:71]([CH3:72])([CH3:73])[C:74]([CH3:75])([CH3:76])[CH3:77])[c:78]1[cH:79][c:80]([OH:89])[cH:81][c:82]2[c:83]1[O:84][CH2:85][C:86](=[O:88])[NH:87]2)[CH2:122][CH2:121][CH2:120][CH2:119][CH2:118][CH2:117][CH2:116][CH2:115][CH2:114][CH2:113][CH2:112][S:109]([c:106]1[cH:105][c:104]([CH3:124])[c:103]2[n:102][cH:101][c:100]([C:125](=[O:126])[NH2:127])[c:99]([NH:98][c:94]3[cH:93][c:92]([O:91][CH3:90])[cH:97][cH:96][cH:95]3)[c:108]2[cH:107]1)(=[O:110])=[O:111]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-e9ac2716b696492eb22e533bb00aec69
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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