3,3-Dimethylbutanoyl chloride → 8-(3,3-Dimethylbutanoyl)-2-(4-(2,2,2-trifluoroethoxy)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione
Reaction equation
[CH3:25][C:26]([CH2:27][C:28](=[O:29])[Cl:30])([CH3:31])[CH3:32].[F:1][C:2]([CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([N:11]2[C:12](=[O:22])[C:13]3([CH2:14][CH2:15]2)[CH2:16][C:17](=[O:21])[NH:18][CH2:19][CH2:20]3)[cH:9][cH:10]1)([F:23])[F:24]>>[F:1][C:2]([CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([N:11]2[C:12](=[O:22])[C:13]3([CH2:14][CH2:15]2)[CH2:16][C:17](=[O:21])[N:18]([C:28]([CH2:27][C:26]([CH3:25])([CH3:31])[CH3:32])=[O:29])[CH2:19][CH2:20]3)[cH:9][cH:10]1)([F:23])[F:24]Participants
3
Sources & evidence
- ORD record
- ord-e9048ed44d6f412ea1e3ba08e5acb049
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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