Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2322431Generated: October 26, 2026

Methyl iodide → 1-tert-Butoxycarbonyl-4-[2-(2-fluoro-4-methoxy-phenylsulfanyl)-5-fluoro-phenyl]-piperidine-4-ol

https://huagongshe.com/reaction/2322431

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant3-Fluoro-4-nitrophenolHCID 520948—
Reactant4-Amino-3-fluorophenolHCID 2735919—
Reactant2-Fluoro-1-iodo-4-methoxybenzeneHCID 21187203—
Reactant4-(5-Fluoro-2-mercapto-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl esterHCID 68682113—
Product1-tert-Butoxycarbonyl-4-[2-(2-fluoro-4-methoxy-phenylsulfanyl)-5-fluoro-phenyl]-piperidine-4-olHCID 68685410—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-374e510e924d48ab96b1773f138e2a5c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)